Reference values for serum ferritin and percentage of transferrin saturation in Korean children and adolescents

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Reference centiles for serum ferritin and percentage of transferrin saturation, with application to mutations of the HFE gene.

BACKGROUND The gene that causes most cases of hereditary hemochromatosis is designated HFE. Individuals with mutations in the HFE gene may have increased serum iron, transferrin saturation, and ferritin concentrations relative to individuals with the wild-type genotype. METHODS We generated reference centiles for percentage of transferrin saturation and serum ferritin concentrations in normal...

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Serum ferritin and transferrin saturation in Asians and Pacific Islanders.

BACKGROUND Asians and Pacific Islanders in the Hemochromatosis and Iron Overload Screening (HEIRS) Study had the highest prevalence of elevated serum ferritin (SF) and transferrin saturation (TS) levels, but to our knowledge, the reasons for this have not been investigated. METHODS Using multiple linear regression, we compared TS and SF distributions for 42 720 Asian, Pacific Islander, and wh...

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Assessing iron status: beyond serum ferritin and transferrin saturation.

The increasing prevalence of multiple comorbidities among anemic patients with chronic kidney disease has made the use of serum ferritin and transferrin saturation more challenging in diagnosing iron deficiency. Because serum ferritin is an acute-phase reactant and because the inflammatory state may inhibit the mobilization of iron from reticuloendothelial stores, the scenario of patients with ...

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Pediatric Reference Intervals for Transferrin Saturation in the CALIPER Cohort of Healthy Children and Adolescents

BACKGROUND Transferrin saturation reference intervals specific for age and sex have not been previously reported for the pediatric population. The reference values for transferrin saturation have been previously reported to be lower in children compared to adults, caused by a combination of low serum iron and high serum transferrin levels in children, warranting specific reference intervals. He...

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Relationship between Serum Ferritin Levels and Dyslipidemia in Korean Adolescents

BACKGROUND Ferritin is associated with various cardiometabolic risk factors such as dyslipidemia, hypertension, obesity, and insulin resistance in adults. We aimed to study the association between serum ferritin levels and dyslipidemia in adolescents, because dyslipidemia is considered an important modifiable cardiovascular risk factor in the young. METHODS We analyzed 1,879 subjects (1,026 b...

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ژورنال

عنوان ژورنال: Blood Research

سال: 2018

ISSN: 2287-979X,2288-0011

DOI: 10.5045/br.2018.53.1.18